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Best Ergonomic Mouse for Big and Large Hands 2023

A big and large hand holding an ergonomic computer mouse.

Are you annoyed by the tiny size of your computer mouse? Do you feel frustrated whenever your big, gigantic hands swallow the mouse every time you try to move it around?

Relax; you’re not alone. Some people are just blessed with massive palms.

Short on time? These are the top picks for the best ergonomic mouse for big and large hands:

Best Ergonomic Features

Anker 2.4G Wireless Vertical Mouse

  • Ergonomic Design
  • Sleek & Modern
  • Improved Tracking

Best Overall Mouse

Logitech M570 Wireless Trackball Mouse

  • Advanced Trackball
  • Long Battery Life
  • Compact Design

Best Economic Mouse

Inphic Large Ergonomic Wireless Mouse

  • Ergonomic Design
  • Sweat Resistant
  • Super Affordable

Because computer mouse devices are designed for normal people, you might have a hard time using them because of your humongous hands. Don’t worry; we understand that this issue may cause discomfort and inconvenience.

That is why, in this article, we have reviewed the best ergonomic mouse for big and large hands. We’ve selected the top of the line devices to make sure that you have a comfortable experience, whether for gaming or professional purposes.

At Office Solution Pro, we are passionate about Ergonomics! Our readers support the page. If you click on a link, we may earn a small commission at no cost to you. We hope you love the products we recommend as much as we do!

Comparison Table

Logitech M570 Wireless Trackball Mouse

Anker 2.4G Wireless Vertical Ergonomic Mouse

Logitech M510 Wireless Computer Mouse

Inphic Large Ergonomic Wireless Mouse

Logitech MX Master 2S Wireless Mouse

Big and Large Ergonomic Mouse Size Guide

You can pretty much figure out if you have big hands just from a glance; however, it’s important to know whether you have medium-sized or large-sized hands to choose the best option available.

Why does the mouse size matter? When you buy a mouse that is too small, your hands will curl up in a clawed position (similar to that of a claw machine) and your fingers will endure the enormous strain over a long period of time.

The same thing applies when you choose a mouse that is too big. Working on an overly-large mouse will force your fingers to stretch out with tension. Over time, pain may start to develop in your hands and wrists.

If you know someone who has small hands, or you’re looking to buy them a perfectly-sized computer mouse, you can show them our list of the best small ergonomic mouse. You can also check out the list to help a friend achieve comfort at work.

Computer Mouse Size Chart

Measuring the size of your hand is very simple. You can use a tape measure or a ruler and measure the length from the tip of your middle finger to the first crease of the wrist (below the palm).

You can use this chart to see how your hand measures up:

Hand LengthHand Size for Mouse
Below 6.75 inches (17 cm)Small
Between 6.75 to 7.5 inches (17 – 19 cm)Medium
Between 7.5 to 8.5 inches (19 – 22 cm)Large
Above 8.5 inches (22 cm)Extra Large

If they are longer than 7.5 inches, then your hands are considered large in size. Perfect! We’ve created this list for anyone who falls under the large and extra-large hands category.

Let’s get started!

Best Ergonomic Mouse for Big and Large Hands Reviews

1. Logitech M570 Wireless Trackball Mouse

The first on our list features one of the best mouse devices from Logitech. Right off the bat, one of the best features of this mouse is the large trackball, sculpted in a way that supports your big hands and allows your palm to stay in one place while moving the cursor without moving your arm.

Here are some of the key features of the Logitech M570 Wireless Trackball Mouse:

  • Amazing Trackball – supports your hand and lets you rest your arm
  • Long Battery Life – up to 18 months of use from a single AA battery
  • Compact Design – because the trackball doesn’t move, it’s perfect for tight workspaces
  • Advanced 2.4GHz Wireless – fast data transmission and virtually no delays
  • Logitech Unifying Technology – connect up to 6 devices

Because of the build, this ergonomic mouse is perfect for anyone with larger hands as it is sculpted with the ultimate trackball, providing comfort and thumb-based control.

If you have a busy desk without a lot of space to work with, this mouse is perfect for you as you can navigate the cursor without ever moving your arms.

Furthermore, the mouse has a very long battery life that can last up to 18 months with a single AA battery. You might even forget that the mouse runs on battery!

Should you need to clean your trackball, removing the ball is a snap and very easy to clean.

With that said, there’s a reason why the Logitech M570 Trackball Mouse is out top pick for the best ergonomic mouse for big hands. It is one of the best-sellers in the market and it’s easy to see why. You can’t go wrong with this mouse and it’s certainly a good way to start off this list.

2023 Update: This mouse has been discontinued by the manufacturer. Get one while you still can. The price is reflective of availability and has gone through the roof!

2. Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

The second on our list features a wireless vertical ergonomic mouse from Anker, one of the mouse devices that offer a unique ergonomic design. What makes this mouse truly wonderful is that it allows your hand to stay in a neutral position, preventing unwanted wrist strains.

These are some of the Anker 2.4G Wireless Vertical Mouse key features:

  • Ergonomic Design – comfortable while avoiding unwanted hand and wrist injuries
  • Sleek and Modern – minimalistic and futuristic design
  • Functional – three levels of mouse sensitivity for improved tracking
  • Easy Access – five buttons give you improved control for different computing needs

It’s important to note that some users have reported that this mouse is too big for their small hands, which is great news for anyone with big and large hands.

Another useful feature of the Anker mouse is its smart power-saving mode, where it will shut down immediately after 8 minutes of inactivity. To power it up, simply press the right or left button.

The Anker mouse is a high, vertical mouse with a height of 3.15 inches. You’ll notice that your hand will stay in the ideal handshake position, allowing you to work without fatigue, as there are no movements of the wrists involved.

In addition to its incredible ergonomic design, another noteworthy feature is the affordable price. You’ll be surprised that Anker Vertical Mouse is available at such a ridiculously low price. No doubt, this is one of the best options for the best ergonomic mouse for large hands.

3. Logitech M510 Wireless Computer Mouse

The third on our list is another offering from Logitech. If you are someone who is not keen on using a trackball, then this ergonomic mouse is perfect for you.

The Logitech M510 Mouse is ergonomically sculpted and designed with a soft rubber grip to conform to your big, right, or left hand, allowing you to be naturally comfortable. Easy to take with you wherever you use your computer at home, work, or anywhere else.

Here are some of the key features of the Logitech M510 Mouse:

  • Comfortable Shape and Grip – contoured shape with soft rubber grip
  • Long battery life – up to 2 years of battery life
  • Convenient Controls – back/forward buttons, side-to-side scrolling, and zoom
  • Precision and Accuracy – precise cursor control and advanced optical tracking
  • Ambidextrous – perfect for right or left hand users

The Logitech M510 Mouse is a bit longer than most ergonomic mouse devices. It will fit your larger hands comfortably, which many smaller mice don’t. The mouse is also pleasantly symmetrical, perfect for right-handed or left-handed users.

Furthermore, you can also choose between three beautiful colors: Black, Blue, or Red. All three are excellent choices to complete the ideal ergonomic workstation.

Another positive feature of the Logitech M510 Mouse is how whisper-quiet it is. You’ll be satisfied with how little noise is made by this mouse. With an affordable price point, this is definitely one of the best ergonomic mouse for big hands.

4. Inphic Large Ergonomic Wireless Mouse

We have a new brand on the fourth entry of our list. The name says it all, the Inphic Large Ergonomic Wireless Mouse is specifically designed for large-sized palms.

Compared to the original design, this mouse is bigger in size while offering the same comfortable and supportive hand feeling.

These are some of the key features of the Inphic Large Ergonomic Wireless Mouse:

  • Ergonomic Design – fits medium to large-sized palms
  • 5 Adjustable CPI and 2 Polling Rate – easily change the cursor sensitivity
  • Strong Durability – 5 million keystroke test
  • Maximum Comfort – beautiful sweat-resistant material

With its sweat-resistant and skin-friendly finish, this mouse is designed for maximum comfort for whatever your needs are. It’s also masterfully contoured to fit the shape of your palms.

Another useful feature from this mouse is the ring/pinkie rest on the side. When using this mouse, the side rest designated for your ring or pinkie finger provides additional support when working all day. This is perfect for your big and large hands.

As one of the best ergonomic mouse for large hands, we admire the insane value delivered by the Inphic Large Ergonomic Mouse because of the price. It’s super affordable when considering all of its amazing features.

5. Logitech MX Master 2S Wireless Mouse

Last but not least, we have the Logitech MX Master 2S Mouse as the final entry on our list. It has a unique ergonomic design that features a large thumb rest to provide maximum support and comfort.

What’s different about this mouse, compared to the others on this list, is that this mouse is rechargeable. This allows you to use the mouse for up to 70 days on a single charge.

Here are some of the key features of the Logitech MX Master 2S Mouse:

  • Ergonomic Comfort – perfectly sculpted and handcrafted for unrivaled comfort
  • Best Quality Tracking – 4000-DPi tracks on any surface, even glass
  • Fast Recharging – full charge can last up to 70 days
  • Hyper-efficient Scrolling – speed-adaptive scroll wheel

In addition, the Logitech MX Master 2S Mouse offers dual connectivity, allowing you to connect your device via the Unifying Receiver or the Bluetooth option.

Thanks to the Logitech Easy-Switch technology, you can pair up to 3 devices and switch between them seamlessly with a touch of a button.

To recharge your battery, you can plug the mouse using the micro-USB charging cable. With a 3-minute charge, it can power you through an entire day of work or gaming. A full charge will last for up to 70 days.

With all the features combined, the Logitech MX Master 2S Mouse is a high-performance mouse as it provides a swift scroll with quick drag. Its hyper-active scrolling and extra buttons make it an excellent choice for gaming.

Taking all things into consideration, the Logitech MX Master 2S Mouse is the most technologically advanced device when compared to the others on the list. Therefore, you’ll get what you pay for. Because of the extensive features, this mouse will cost you the most money.

Honorable Mention Big Ergonomic Mouse

AUTLEY Wireless Ergonomic Mouse

While we finished the best ergonomic mouse for big and large hands list with the above top 5, we have to give a special nod to the AUTLEY Ergonomic Mouse as it truly embodies what it means to be a big wireless mouse.

These are the key features that make the AUTLEY Wireless Ergonomic Mouse stands out:

  • Large Ergonomic Design – vertical design promoting neutral hand position
  • Adjustable Sensitivity – three levels of mouse sensitivity for improved tracking
  • Smooth Matte Coating – comfortable to the touch and anti-slip material
  • Strong Durability – 5 million keystroke test

AUTLEY’s mouse claim to fame is that it’s built specifically for big and large hands. Even the manufacturers stated that this mouse might not suit women and small hands. After giving this mouse a test run, we have to agree it’s huge!

We have to admit that it did take several days to get used to the shape of this mouse. However, once you get into the swing of things, this mouse is truly comfortable to work on for long periods of time.

Compared to other conventional mice, the AUTLEY Ergonomic Mouse provides a pinkie finger rest on the side, while its vertical design promotes a neutral handshake position. Your fingers will not touch the desk at all, allowing you to achieve maximum comfort for long hours each day.

A fancy feature added by AUTLEY is the blue backlight below the mouse that gives it a touch of charm and modern-look on top of the smooth matte material covering the whole mouse. It feels truly comfortable as it is anti-slip and provides maximum grip to the mouse.

One downside, however, is the not-so-great battery power. A full charge of 2 hours will only last you up to 12-20 days of moderate use. Compared to the top 5 on the list, surely AUTLEY can do a much better job. This is one of the reasons why this mouse missed the cut, although, it is worth mentioning.

However, we’ve had many users that have reported significant improvement in their wrist pain after switching to the AUTLEY Ergonomic Mouse. If you have large palms, and comfort is your number one priority, then this mouse is definitely for you.

Overall, it’s not a mouse that will blow your minds away with extensive features, but given the affordable price, the AUTLEY Ergonomic Mouse is a solid pick for the best ergonomic mouse for large hands that can get the job done.

Related: Different Types of Computer Mouse Explained

Final Verdict

And there you have it, a complete list with the best ergonomic mouse for big and large hands. Our team curated this special list for all of you with massive hands because we do not want you guys to feel left out.

If you are keen on buying a large mouse with an amazing trackball, definitely buy the Logitech M570.

If you are looking for a long ergonomic mouse, go for the Logitech M510. This is also the only ambidextrous or symmetrical mouse on this list.

If you want to buy the best big mouse for its value, check out the Inphic Large Ergonomic Mouse.

Hopefully, by taking the time to read this list, every single one of you who are blessed with giant palms will be able to choose the best mouse device for your daily professional and office needs. Cheers! 🙂

PS: Remember to maintain your new mouse so that it will last for years to come. We have an extensive guide for you to read on how to clean your computer mouse.

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